Immune cytopenias as the presenting finding in primary Sjögren's syndrome
Identifieur interne : 002532 ( Main/Exploration ); précédent : 002531; suivant : 002533Immune cytopenias as the presenting finding in primary Sjögren's syndrome
Auteurs : A. Schattner ; J. Friedman ; A. Klepfish [Israël] ; A. Berrebi [Israël]Source :
- QJM [ 1460-2725 ] ; 2000.
Abstract
A diagnostic delay of several years in primary Sjögren's syndrome is common, even in patients who present with sicca symptoms. It is much more likely in cases with prominent symptomatic extraglandular involvement. We report on three such patients who presented as Coomb's positive haemolytic anaemia, systemic symptoms with agranulocytosis and gingival bleeding due to immune thrombocytopenia, to alert clinicians to the fact that primary Sjögren's syndrome may present as clinically significant immune‐mediated cytopenia in the absence of sicca symptoms. Sjögren's syndrome, a common autoimmune disorder, should be considered in the differential diagnosis of apparently ‘idiopathic’ cytopenias and actively sought by directed history, Schirmer test and autoantibody screening.
Url:
DOI: 10.1093/qjmed/93.12.825
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001746
- to stream Istex, to step Curation: 001746
- to stream Istex, to step Checkpoint: 001350
- to stream Main, to step Merge: 002560
- to stream Main, to step Curation: 002532
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immune cytopenias as the presenting finding in primary Sjögren's syndrome</title><author><name sortKey="Schattner, A" sort="Schattner, A" uniqKey="Schattner A" first="A." last="Schattner">A. Schattner</name></author><author><name sortKey="Friedman, J" sort="Friedman, J" uniqKey="Friedman J" first="J." last="Friedman">J. Friedman</name></author><author><name sortKey="Klepfish, A" sort="Klepfish, A" uniqKey="Klepfish A" first="A." last="Klepfish">A. Klepfish</name></author><author><name sortKey="Berrebi, A" sort="Berrebi, A" uniqKey="Berrebi A" first="A." last="Berrebi">A. Berrebi</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:7DD6EDF30DCB6CB7636F43A482A6251ABD28BCBC</idno><date when="2000" year="2000">2000</date><idno type="doi">10.1093/qjmed/93.12.825</idno><idno type="url">https://api.istex.fr/ark:/67375/HXZ-VD900BJM-W/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001746</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001746</idno><idno type="wicri:Area/Istex/Curation">001746</idno><idno type="wicri:Area/Istex/Checkpoint">001350</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001350</idno><idno type="wicri:doubleKey">1460-2725:2000:Schattner A:immune:cytopenias:as</idno><idno type="wicri:Area/Main/Merge">002560</idno><idno type="wicri:Area/Main/Curation">002532</idno><idno type="wicri:Area/Main/Exploration">002532</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Immune cytopenias as the presenting finding in primary Sjögren's syndrome</title><author><name sortKey="Schattner, A" sort="Schattner, A" uniqKey="Schattner A" first="A." last="Schattner">A. Schattner</name></author><author><name sortKey="Friedman, J" sort="Friedman, J" uniqKey="Friedman J" first="J." last="Friedman">J. Friedman</name></author><author><name sortKey="Klepfish, A" sort="Klepfish, A" uniqKey="Klepfish A" first="A." last="Klepfish">A. Klepfish</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Hematology Unit, Kaplan Medical Center, Rehovot, and the Hebrew University‐Hadassah Medical School, Jerusalem</wicri:regionArea><wicri:noRegion>Jerusalem</wicri:noRegion></affiliation></author><author><name sortKey="Berrebi, A" sort="Berrebi, A" uniqKey="Berrebi A" first="A." last="Berrebi">A. Berrebi</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Hematology Unit, Kaplan Medical Center, Rehovot, and the Hebrew University‐Hadassah Medical School, Jerusalem</wicri:regionArea><wicri:noRegion>Jerusalem</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">QJM</title><title level="j" type="abbrev">QJM</title><idno type="ISSN">1460-2725</idno><idno type="eISSN">1460-2393</idno><imprint><publisher>Oxford University Press</publisher><date when="2000-12">2000</date><biblScope unit="vol">93</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="825">825</biblScope><biblScope unit="page" to="829">829</biblScope></imprint><idno type="ISSN">1460-2725</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1460-2725</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A diagnostic delay of several years in primary Sjögren's syndrome is common, even in patients who present with sicca symptoms. It is much more likely in cases with prominent symptomatic extraglandular involvement. We report on three such patients who presented as Coomb's positive haemolytic anaemia, systemic symptoms with agranulocytosis and gingival bleeding due to immune thrombocytopenia, to alert clinicians to the fact that primary Sjögren's syndrome may present as clinically significant immune‐mediated cytopenia in the absence of sicca symptoms. Sjögren's syndrome, a common autoimmune disorder, should be considered in the differential diagnosis of apparently ‘idiopathic’ cytopenias and actively sought by directed history, Schirmer test and autoantibody screening.</div></front></TEI><affiliations><list><country><li>Israël</li></country></list><tree><noCountry><name sortKey="Friedman, J" sort="Friedman, J" uniqKey="Friedman J" first="J." last="Friedman">J. Friedman</name><name sortKey="Schattner, A" sort="Schattner, A" uniqKey="Schattner A" first="A." last="Schattner">A. Schattner</name></noCountry><country name="Israël"><noRegion><name sortKey="Klepfish, A" sort="Klepfish, A" uniqKey="Klepfish A" first="A." last="Klepfish">A. Klepfish</name></noRegion><name sortKey="Berrebi, A" sort="Berrebi, A" uniqKey="Berrebi A" first="A." last="Berrebi">A. Berrebi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002532 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002532 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:7DD6EDF30DCB6CB7636F43A482A6251ABD28BCBC
|texte= Immune cytopenias as the presenting finding in primary Sjögren's syndrome
}}
| This area was generated with Dilib version V0.6.33. |  |